Mouse Trpc2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Trpc2
Locus ID	22064
Kit Components	GA204453G1, Trpc2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204453G2, Trpc2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204453G3, Trpc2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001109897
Synonyms	3010009O07Rik; AI115608; mTrp2; smTRPC2; trp2; TRPC2a; TRPC2b; Trrp2
Summary	Thought to form a receptor-activated non-selective calcium permeant cation channel. Probably is operated by a phosphatidylinositol second messenger system activated by receptor tyrosine kinases or G-protein coupled receptors. May also be activated by intracellular calcium store depletion. Plays a role in mediating responsivity to pheromones that elicit aggressive and mating behaviors. Required for response to the Esp1 pheromone which enhances female sexual receptive behavior and to the Esp22 pheromone which inhibits adult male mating behavior.[UniProtKB/Swiss-Prot Function]

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