Mouse Tulp3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tulp3
Locus ID	22158
Kit Components	GA204497G1, Tulp3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204497G2, Tulp3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204497G3, Tulp3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011657
Synonyms	2310022L06Rik; AI316887
Summary	Negative regulator of the Shh signaling transduction pathway: recruited to primary cilia via association with the IFT complex A (IFT-A) and is required for recruitment of G protein-coupled receptor GPR161 to cilia, a promoter of PKA-dependent basal repression machinery in Shh signaling. Binds to phosphorylated inositide (phosphoinositide) lipids. Both IFT-A- and phosphoinositide-binding properties are required to regulate ciliary G protein-coupled receptor trafficking. Not involved in ciliogenesis.[UniProtKB/Swiss-Prot Function]

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