Mouse Uros activation kit by CRISPRa

CAT#: GA204559

Uros CRISPRa kit - CRISPR gene activation of mouse uroporphyrinogen III synthase



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Uros
Locus ID 22276
Kit Components

GA204559G1, Uros gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA204559G2, Uros gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA204559G3, Uros gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_001302085, NM_001302086, NM_001302087, NM_009479, NR_153415, NR_153416
Synonyms AI415298; UROIIIS; Uros3
Summary The protein encoded by this gene is the fourth enzyme in the heme biosynthesis pathway. It converts hydroxymethylbilane to uroporphyrinogen III, a cyclic tetrapyrrole. This enzyme is defective in the autosomal recessive disorder congenital erythropoietic porphyria. Alternate promoter usage controls cell type-specific expression, including erythroid cell-specific expression. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Sep 2014]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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