Mouse Vldlr activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Vldlr
Locus ID	22359
Kit Components	GA204604G1, Vldlr gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204604G2, Vldlr gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204604G3, Vldlr gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001161420, NM_001347441, NM_013703
Synonyms	AA408956; AI451093; AW047288
Summary	Binds VLDL and transports it into cells by endocytosis. In order to be internalized, the receptor-ligand complexes must first cluster into clathrin-coated pits. Binding to Reelin induces tyrosine phosphorylation of Dab1 and modulation of Tau phosphorylation.[UniProtKB/Swiss-Prot Function]

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