Mouse Wnt3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Wnt3
Locus ID	22415
Kit Components	GA204637G1, Wnt3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204637G2, Wnt3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204637G3, Wnt3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009521
Synonyms	Int-4; Wnt-3
Summary	Ligand for members of the frizzled family of seven transmembrane receptors (Probable). Functions in the canonical Wnt signaling pathway that results in activation of transcription factors of the TCF/LEF family (By similarity). Required for normal gastrulation, formation of the primitive streak, and for the formation of the mesoderm during early embryogenesis (PubMed:10431240). Required for normal formation of the apical ectodermal ridge and for normal embryonic limb development (PubMed:12569130).[UniProtKB/Swiss-Prot Function]

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