Mouse Wnt7b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Wnt7b
Locus ID	22422
Kit Components	GA204644G1, Wnt7b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204644G2, Wnt7b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204644G3, Wnt7b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001163633, NM_001163634, NM_009528
Synonyms	Wnt-7b
Summary	Ligand for members of the frizzled family of seven transmembrane receptors that functions in the canonical Wnt/beta-catenin signaling pathway (PubMed:15923619, PubMed:28803732). Required for normal fusion of the chorion and the allantois during placenta development (PubMed:11543617). Required for central nervous system (CNS) angiogenesis and blood-brain barrier regulation (PubMed:28803732).[UniProtKB/Swiss-Prot Function]

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