Mouse Xrcc1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Xrcc1
Locus ID	22594
Kit Components	GA204660G1, Xrcc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204660G2, Xrcc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204660G3, Xrcc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_009532, NM_001360170, NM_001360168, NM_001360169
Synonyms	Xrcc-1
Summary	Involved in DNA single-strand break repair by mediating the assembly of DNA break repair protein complexes (By similarity). Probably during DNA repair, negatively regulates ADP-ribose levels by modulating ADP-ribosyltransferase PARP1 activity (PubMed:28002403).[UniProtKB/Swiss-Prot Function]

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