Mouse Ash2l activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ash2l
Locus ID	23808
Kit Components	GA204765G1, Ash2l gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204765G2, Ash2l gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204765G3, Ash2l gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001080793, NM_001286207, NM_011791, NM_001359012
Summary	Component of the Set1/Ash2 histone methyltransferase (HMT) complex, a complex that specifically methylates 'Lys-4' of histone H3, but not if the neighboring 'Lys-9' residue is already methylated. As part of the MLL1/MLL complex it is involved in methylation and dimethylation at 'Lys-4' of histone H3. May function as a transcriptional regulator. May play a role in hematopoiesis (By similarity).[UniProtKB/Swiss-Prot Function]

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