Mouse Impdh1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Impdh1
Locus ID	23917
Kit Components	GA204809G1, Impdh1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204809G2, Impdh1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204809G3, Impdh1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001302933, NM_001302934, NM_011829
Synonyms	B930086D20Rik; IMPDH-I
Summary	Catalyzes the conversion of inosine 5'-phosphate (IMP) to xanthosine 5'-phosphate (XMP), the first committed and rate-limiting step in the de novo synthesis of guanine nucleotides, and therefore plays an important role in the regulation of cell growth. Could also have a single-stranded nucleic acid-binding activity and could play a role in RNA and/or DNA metabolism. It may also have a role in the development of malignancy and the growth progression of some tumors.[UniProtKB/Swiss-Prot Function]

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