Mouse Aadat activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Aadat
Locus ID	23923
Kit Components	GA204815G1, Aadat gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204815G2, Aadat gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204815G3, Aadat gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_011834
Synonyms	Aadt; AI875679; Kat2; KATII; Kyat2; mKat-2
Summary	Transaminase with broad substrate specificity. Has transaminase activity towards aminoadipate, kynurenine, methionine and glutamate. Shows activity also towards tryptophan, aspartate and hydroxykynurenine. Accepts a variety of oxo-acids as amino-group acceptors, with a preference for 2-oxoglutarate, 2-oxocaproic acid, phenylpyruvate and alpha-oxo-gamma-methiol butyric acid. Can also use glyoxylate as amino-group acceptor (in vitro) (By similarity).[UniProtKB/Swiss-Prot Function]

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