Mouse Tlk2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tlk2
Locus ID	24086
Kit Components	GA204894G1, Tlk2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204894G2, Tlk2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204894G3, Tlk2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001112705, NM_001294329, NM_001294330, NM_001294331, NM_001294334, NM_011903, NM_001361996
Synonyms	4933403M19Rik; PKU-alpha; PKUalpha; Tlk
Summary	Serine/threonine-protein kinase involved in the process of chromatin assembly and probably also DNA replication, transcription, repair, and chromosome segregation. Phosphorylates the chromatin assembly factors ASF1A AND ASF1B. Phosphorylation of ASF1A prevents its proteasome-mediated degradation, thereby enhancing chromatin assembly (By similarity). Negative regulator of amino acid starvation-induced autophagy (By similarity).[UniProtKB/Swiss-Prot Function]

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