Mouse Ifi202b activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ifi202b
Locus ID	26388
Kit Components	GA204940G1, Ifi202b gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204940G2, Ifi202b gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204940G3, Ifi202b gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_008327, NM_011940
Synonyms	Ifbip-1; Ifi202; Ifi202a; p202
Summary	Inhibits the transcriptional activity of several transcription factors, including NF-kappa-B p50 and p65, FOS, JUN, E2F1, E2F4, MYOD1 and myogenin. Has anti-apoptotic effects due to inhibition of the transcriptional activity of p53. Binds dsDNA in the cytosol. Is involved in innate immune response and has anti-inflammatory activity. Inhibits caspase activation in response to cytosolic DNA and inhibits the activation of the AIM2 inflammasome, probably by sequestering cytoplasmic DNA and preventing its being bound by AIM2.[UniProtKB/Swiss-Prot Function]

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