Mouse Map3k12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Map3k12
Locus ID	26404
Kit Components	GA204949G1, Map3k12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA204949G2, Map3k12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA204949G3, Map3k12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001163643, NM_009582, NM_001358844
Synonyms	DLK; MUK; Zpk
Summary	Protein kinase which is part of a non-canonical MAPK signaling pathway (PubMed:7983011, PubMed:8663324, PubMed:28111074). Activated by APOE, enhances the AP-1-mediated transcription of APP, via a MAP kinase signal transduction pathway composed of MAP2K7 and MAPK1/ERK2 and MAPK3/ERK1 (PubMed:28111074). May be an activator of the JNK/SAPK pathway.[UniProtKB/Swiss-Prot Function]

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