Mouse Dguok activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Dguok
Locus ID	27369
Kit Components	GA205129G1, Dguok gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205129G2, Dguok gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205129G3, Dguok gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001162521, NM_013764, NR_149734
Synonyms	dGK; dGK1; dGK2; dGK3
Summary	Phosphorylates deoxyguanosine and deoxyadenosine in the mitochondrial matrix, with the highest efficiency for deoxyguanosine. In non-replicating cells, where cytosolic dNTP synthesis is down-regulated, mtDNA synthesis depends solely on DGUOK and TK2. Phosphorylates certain nucleoside analogs. Widely used as target of antiviral and chemotherapeutic agents.[UniProtKB/Swiss-Prot Function]

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