Mouse Spdef activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Spdef
Locus ID	30051
Kit Components	GA205257G1, Spdef gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205257G2, Spdef gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205257G3, Spdef gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_013891, NM_001357728
Synonyms	PDEF; Pse
Summary	May function as an androgen-independent transactivator of the prostate-specific antigen (PSA) promoter. Binds to 5'-GGAT-3' DNA sequences. May play a role in the regulation of the prostate gland and/or prostate cancer development. Acts as a transcriptional activator for SERPINB5 promoter (By similarity).[UniProtKB/Swiss-Prot Function]

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