Mouse Magi2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Magi2
Locus ID	50791
Kit Components	GA205371G1, Magi2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205371G2, Magi2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205371G3, Magi2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001170745, NM_001170746, NM_015823
Synonyms	Acvri1; Acvrinp1; Acvrip1; AIP-1; Magi-2; mKIAA0705; S-SCAM
Summary	Seems to act as scaffold molecule at synaptic junctions by assembling neurotransmitter receptors and cell adhesion proteins. Plays a role in nerve growth factor (NGF)-induced recruitment of RAPGEF2 to late endosomes and neurite outgrowth. May play a role in regulating activin-mediated signaling in neuronal cells. Enhances the ability of PTEN to suppress AKT1 activation (By similarity).[UniProtKB/Swiss-Prot Function]

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