Mouse Setd3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Setd3
Locus ID	52690
Kit Components	GA205509G1, Setd3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205509G2, Setd3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205509G3, Setd3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_028262, NM_001364266, NM_001364267, NM_001364268, NM_001364269, NM_001364270
Synonyms	2610102I01Rik; 2610305M23Rik; 6030490B17Rik; D12Ertd771e
Summary	Protein-histidine N-methyltransferase that specifically mediates methylation of actin at 'His-73' (PubMed:30626964). Histidine methylation of actin is required for smooth muscle contraction of the laboring uterus during delivery (PubMed:30626964). Does not have protein-lysine N-methyltransferase activity and probably only catalyzes histidine methylation of actin (PubMed:30626964).[UniProtKB/Swiss-Prot Function]

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