Mouse Slx4 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slx4
Locus ID	52864
Kit Components	GA205531G1, Slx4 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205531G2, Slx4 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205531G3, Slx4 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_177472
Synonyms	AI256635; AI426760; Btbd12; D16Bwg1016e
Summary	This gene encodes a protein containing a BTB (POZ) domain that comprises a subunit of structure-specific endonucleases. The encoded protein aids in the resolution of DNA secondary structures that arise during the processes of DNA repair and recombination. Knock out of this gene in mouse recapitulates the phenotype of the human disease Fanconi anemia, including blood cytopenia and susceptibility to genomic instability. [provided by RefSeq, Dec 2013]

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