Mouse Rgs7bp activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rgs7bp
Locus ID	52882
Kit Components	GA205533G1, Rgs7bp gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205533G2, Rgs7bp gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205533G3, Rgs7bp gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_029879
Synonyms	A930030I01Rik; AI842293; D13Bwg1146e; R7bp
Summary	Regulator of G protein-coupled receptor (GPCR) signaling. Regulatory subunit of the R7-Gbeta5 complexes that acts by controlling the subcellular location of the R7-Gbeta5 complexes. When palmitoylated, it targets the R7-Gbeta5 complexes to the plasma membrane, leading to inhibit G protein alpha subunits. When it is unpalmitoylated, the R7-Gbeta5 complexes undergo a nuclear/cytoplasmic shuttling. May also act by controlling the proteolytic stability of R7 proteins, probably by protecting them from degradation.[UniProtKB/Swiss-Prot Function]

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