Mouse Pla2g6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pla2g6
Locus ID	53357
Kit Components	GA205558G1, Pla2g6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205558G2, Pla2g6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205558G3, Pla2g6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001199023, NM_001199024, NM_001199025, NM_016915
Synonyms	BB112799; iPLA(2)beta; iPLA2; iPLA2beta; PNPLA9
Summary	Catalyzes the release of fatty acids from phospholipids. It has been implicated in normal phospholipid remodeling, nitric oxide-induced or vasopressin-induced arachidonic acid release and in leukotriene and prostaglandin production. May participate in fas mediated apoptosis and in regulating transmembrane ion flux in glucose-stimulated B-cells. Has a role in cardiolipin (CL) deacylation. Required for both speed and directionality of monocyte MCP1/CCL2-induced chemotaxis through regulation of F-actin polymerization at the pseudopods (By similarity).[UniProtKB/Swiss-Prot Function]

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