Mouse Ccrl2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ccrl2
Locus ID	54199
Kit Components	GA205663G1, Ccrl2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205663G2, Ccrl2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205663G3, Ccrl2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001302376, NM_001302377, NM_017466
Synonyms	1810047I05Rik; Ackr5; CCR11; Cmkbr1l2; E01; L-CCR
Summary	Receptor for CCL19 and chemerin/RARRES2. Does not appear to be a signaling receptor, but may have a role in modulating chemokine-triggered immune responses by capturing and internalizing CCL19 or by presenting RARRES2 ligand to CMKLR1, a functional signaling receptor. Plays a critical role for the development of Th2 responses (By similarity).[UniProtKB/Swiss-Prot Function]

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