Mouse Elp5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Elp5
Locus ID	54351
Kit Components	GA205676G1, Elp5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205676G2, Elp5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205676G3, Elp5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001253700, NM_018740, NR_027884, NR_027977
Synonyms	Derp6; Rai12
Summary	Acts as subunit of the RNA polymerase II elongator complex, which is a histone acetyltransferase component of the RNA polymerase II (Pol II) holoenzyme and is involved in transcriptional elongation. Elongator may play a role in chromatin remodeling and is involved in acetylation of histones H3 and probably H4. May be involved in TP53-mediated transcriptional regulation. Involved in cell migration.[UniProtKB/Swiss-Prot Function]

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