Mouse St3gal6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	St3gal6
Locus ID	54613
Kit Components	GA205737G1, St3gal6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205737G2, St3gal6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205737G3, St3gal6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018784, NM_001357433, NM_001357434, NM_001357435
Synonyms	1700023B24Rik; AI930218; AW552396; Siat10; St3galVI
Summary	Involved in the synthesis of sialyl-paragloboside, a precursor of sialyl-Lewis X determinant. Has a alpha-2,3-sialyltransferase activity toward Gal-beta1,4-GlcNAc structure on glycoproteins and glycolipids. Has a restricted substrate specificity, it utilizes Gal-beta1,4-GlcNAc on glycoproteins, and neolactotetraosylceramide and neolactohexaosylceramide, but not lactotetraosylceramide, lactosylceramide or asialo-GM1 (By similarity).[UniProtKB/Swiss-Prot Function]

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