Mouse Ap3m1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Ap3m1
Locus ID	55946
Kit Components	GA205780G1, Ap3m1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205780G2, Ap3m1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205780G3, Ap3m1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_018829
Synonyms	1200013D09Rik; C78982; R75378
Summary	Part of the AP-3 complex, an adaptor-related complex which is not clathrin-associated. The complex is associated with the Golgi region as well as more peripheral structures. It facilitates the budding of vesicles from the Golgi membrane and may be directly involved in trafficking to lysosomes. In concert with the BLOC-1 complex, AP-3 is required to target cargos into vesicles assembled at cell bodies for delivery into neurites and nerve terminals.[UniProtKB/Swiss-Prot Function]

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