Mouse Shoc2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Shoc2
Locus ID	56392
Kit Components	GA205943G1, Shoc2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205943G2, Shoc2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205943G3, Shoc2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001168505, NM_019658, NM_001355242
Synonyms	AU017287; mKIAA0862; Sur8
Summary	Regulatory subunit of protein phosphatase 1 (PP1c) that acts as a M-Ras/MRAS effector and participates in MAPK pathway activation. Upon M-Ras/MRAS activation, targets PP1c to specifically dephosphorylate the 'Ser-259' inhibitory site of RAF1 kinase and stimulate RAF1 activity at specialized signaling complexes.[UniProtKB/Swiss-Prot Function]

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