Mouse Pdcd10 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pdcd10
Locus ID	56426
Kit Components	GA205961G1, Pdcd10 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA205961G2, Pdcd10 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA205961G3, Pdcd10 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_019745
Synonyms	2410003B13Rik; Ccm3; Tfa15; Tfar15
Summary	Promotes cell proliferation. Modulates apoptotic pathways. Increases mitogen-activated protein kinase activity and STK26 activity. Important for cell migration, and for normal structure and assembly of the Golgi complex (By similarity). Important for KDR/VEGFR2 signaling. Increases the stability of KDR/VEGFR2 and prevents its breakdown. Required for normal cardiovascular development. Required for normal angiogenesis, vasculogenesis and hematopoiesis during embryonic development (By similarity).[UniProtKB/Swiss-Prot Function]

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