Mouse Aldh1a3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Aldh1a3
Locus ID	56847
Kit Components	GA206110G1, Aldh1a3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206110G2, Aldh1a3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206110G3, Aldh1a3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_053080
Synonyms	ALDH6; RALDH3; V1
Summary	NAD-dependent aldehyde dehydrogenase that catalyzes the formation of retinoic acid (PubMed:11044606, PubMed:11013254, PubMed:14623956). Has high activity with all-trans retinal, and has much lower in vitro activity with acetaldehyde (By similarity). Required for the biosynthesis of normal levels of retinoic acid in the embryonic ocular and nasal regions; retinoic acid is required for normal embryonic development of the eye and the nasal region (PubMed:14623956).[UniProtKB/Swiss-Prot Function]

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