Mouse Pdxp activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pdxp
Locus ID	57028
Kit Components	GA206125G1, Pdxp gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206125G2, Pdxp gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206125G3, Pdxp gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_020271
Synonyms	1600027H05Rik; AB041662; PLPP
Summary	Protein serine phosphatase that dephosphorylates 'Ser-3' in cofilin and probably also dephosphorylates phospho-serine residues in DSTN. Regulates cofilin-dependent actin cytoskeleton reorganization. Required for normal progress through mitosis and normal cytokinesis. Does not dephosphorylate phospho-threonines in LIMK1. Does not dephosphorylate peptides containing phospho-tyrosine (By similarity). Pyridoxal phosphate (PLP) phosphatase, which also catalyzes the dephosphorylation of pyridoxine 5'-phosphate (PNP) and pyridoxamine 5'-phosphate (PMP), with order of substrate preference PLP > PNP > PMP (By similarity) (PubMed:24338473, PubMed:24338687).[UniProtKB/Swiss-Prot Function]

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