Mouse Gtf2ird1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Gtf2ird1
Locus ID	57080
Kit Components	GA206126G1, Gtf2ird1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206126G2, Gtf2ird1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206126G3, Gtf2ird1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001081462, NM_001081463, NM_001081464, NM_001081465, NM_001081466, NM_001081467, NM_001081468, NM_001081469, NM_001081470, NM_001244936, NM_001347488, NM_020331
Synonyms	1700012P16Rik; BEN; Cream1; ESTM9; Gtf2il; GTF3; MusTRD1; Tg(Alb1-Myc)166.8Sst; WBSCR11; X83320
Summary	May be a transcription regulator involved in cell-cycle progression and skeletal muscle differentiation. May repress GTF2I transcriptional functions, by preventing its nuclear residency, or by inhibiting its transcriptional activation. May contribute to slow-twitch fiber type specificity during myogenesis and in regenerating muscles. Binds troponin I slow-muscle fiber enhancer (USE B1). Binds specifically and with high affinity to the EFG sequences derived from the early enhancer of HOXC8.[UniProtKB/Swiss-Prot Function]

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