Mouse Rangrf activation kit by CRISPRa
CAT#: GA206224
Rangrf CRISPRa kit - CRISPR gene activation of mouse RAN guanine nucleotide release factor
CNY 12255.00
Specifications
Product Data | |
Format | 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug) |
Symbol | Rangrf |
Locus ID | 57785 |
Kit Components | GA206224G1, Rangrf gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206224G2, Rangrf gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206224G3, Rangrf gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077 |
Reference Data | |
RefSeq | NM_001285441, NM_001285442, NM_001285443, NM_021329 |
Synonyms | 2400006H24Rik; Mog1; Rangnrf |
Summary | May regulate the intracellular trafficking of RAN (PubMed:10811801, PubMed:11733047). Promotes guanine nucleotide release from RAN and inhibits binding of new GTP by preventing the binding of the RAN guanine nucleotide exchange factor RCC1 (PubMed:10811801, PubMed:11733047). Regulates the levels of GTP-bound RAN in the nucleus, and thereby plays a role in the regulation of RAN-dependent mitotic spindle dynamics (By similarity). Enhances the expression of SCN5A at the cell membrane in cardiomyocytes (PubMed:18184654, PubMed:23420830).[UniProtKB/Swiss-Prot Function] |
Documents
Resources
基因表达相关资源 |
Other Versions
SKU | Description | Size | Price |
---|---|---|---|
KN514463 | Rangrf - KN2.0, Mouse gene knockout kit via CRISPR, non-homology mediated. |
CNY 8680.00 |