Mouse Rgs20 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Rgs20
Locus ID	58175
Kit Components	GA206248G1, Rgs20 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206248G2, Rgs20 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206248G3, Rgs20 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001177795, NM_001290372, NM_021374
Synonyms	2900073E09Rik; Rgsz1
Summary	Inhibits signal transduction by increasing the GTPase activity of G protein alpha subunits thereby driving them into their inactive GDP-bound form. Binds selectively to G(z)-alpha and G(alpha)-i2 subunits, accelerates their GTPase activity and regulates their signaling activities. The G(z)-alpha activity is inhibited by the phosphorylation and palmitoylation of the G-protein. Negatively regulates mu-opioid receptor-mediated activation of the G-proteins.[UniProtKB/Swiss-Prot Function]

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