Mouse Trem1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Trem1
Locus ID	58217
Kit Components	GA206269G1, Trem1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206269G2, Trem1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206269G3, Trem1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001347399, NM_021406
Summary	Stimulates neutrophil and monocyte-mediated inflammatory responses. Triggers release of pro-inflammatory chemokines and cytokines, as well as increased surface expression of cell activation markers. Amplifier of inflammatory responses that are triggered by bacterial and fungal infections and is a crucial mediator of septic shock (By similarity).[UniProtKB/Swiss-Prot Function]

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