Mouse Nudt11 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Nudt11
Locus ID	58242
Kit Components	GA206285G1, Nudt11 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206285G2, Nudt11 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206285G3, Nudt11 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_021431
Synonyms	DIPP3; DIPP3b
Summary	Cleaves a beta-phosphate from the diphosphate groups in PP-InsP5 (diphosphoinositol pentakisphosphate), suggesting that it may play a role in signal transduction. Also able to catalyze the hydrolysis of dinucleoside oligophosphates, with Ap6A and Ap5A being the preferred substrates. The major reaction products are ADP and p4a from Ap6A and ADP and ATP from Ap5A. Also able to hydrolyze 5-phosphoribose 1-diphosphate; however, the relevance of such activity in vivo remains unclear.[UniProtKB/Swiss-Prot Function]

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