Mouse Cdc42ep5 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Cdc42ep5
Locus ID	58804
Kit Components	GA206300G1, Cdc42ep5 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206300G2, Cdc42ep5 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206300G3, Cdc42ep5 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_021454
Synonyms	1700027J19Rik; 2010007O02Rik; Borg3; C85526; CEP5
Summary	Probably involved in the organization of the actin cytoskeleton. May act downstream of CDC42 to induce actin filament assembly leading to cell shape changes. Induces pseudopodia formation in fibroblasts. Inhibits MAPK8 independently of CDC42 binding. Controls septin organization and this effect is negatively regulated by CDC42.[UniProtKB/Swiss-Prot Function]

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