Mouse Lpin2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Lpin2
Locus ID	64898
Kit Components	GA206496G1, Lpin2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206496G2, Lpin2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206496G3, Lpin2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001164885, NM_022882, NM_001357791
Synonyms	2610511G02Rik; AI481352; AW742896
Summary	Plays important roles in controlling the metabolism of fatty acids at different levels. Acts as a magnesium-dependent phosphatidate phosphatase enzyme which catalyzes the conversion of phosphatidic acid to diacylglycerol during triglyceride, phosphatidylcholine and phosphatidylethanolamine biosynthesis in the reticulum endoplasmic membrane. Acts also as a nuclear transcriptional coactivator for PPARGC1A to modulate lipid metabolism.[UniProtKB/Swiss-Prot Function]

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