Mouse Zfand6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Zfand6
Locus ID	65098
Kit Components	GA206508G1, Zfand6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206508G2, Zfand6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206508G3, Zfand6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_022985, NM_001360577, NM_001360578, NM_001360579, NM_001360580, NM_001360581, NM_001360582
Synonyms	3110005P07Rik; Awp1; Za20d3
Summary	Involved in regulation of TNF-alpha induced NF-kappa-B activation and apoptosis. Involved in modulation of 'Lys-48'-linked polyubiquitination status of TRAF2 and decreases association of TRAF2 with RIPK1 (By similarity). Required for PTS1 target sequence-dependent protein import into peroxisomes and PEX5 stability; may cooperate with PEX6. In vitro involved in PEX5 export from the cytosol to peroxisomes.[UniProtKB/Swiss-Prot Function]

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