Mouse Retreg1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Retreg1
Locus ID	66270
Kit Components	GA206678G1, Retreg1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206678G2, Retreg1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206678G3, Retreg1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001034851, NM_001277315, NM_001277316, NM_001277317, NM_001277318, NM_025459
Synonyms	1810015C04Rik; AU015349
Summary	Endoplasmic reticulum-anchored autophagy receptor that mediates ER delivery into lysosomes through sequestration into autophagosomes (PubMed:26040720). Promotes membrane remodeling and ER scission via its membrane bending capacity and targets the fragments into autophagosomes via interaction with ATG8 family proteins (PubMed:26040720). Required for long-term survival of nociceptive and autonomic ganglion neurons (PubMed:19838196, PubMed:26040720).[UniProtKB/Swiss-Prot Function]

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