Mouse Pspc1 activation kit by CRISPRa

CAT#: GA206884

Pspc1 CRISPRa kit - CRISPR gene activation of mouse paraspeckle protein 1



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CNY 12255.00


货期*
4周

规格
    • 1 kit

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Specifications

Product Data
Format 3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol Pspc1
Locus ID 66645
Kit Components

GA206884G1, Pspc1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa

GA206884G2, Pspc1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa

GA206884G3, Pspc1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa

1 CRISPRa-Enhancer vector, SKU GE100056

1 CRISPRa scramble vector, SKU GE100077

Reference Data
RefSeq NM_025682, NM_001360420
Synonyms 5730470C09Rik; AI327109; AI449052; PSP1
Summary Together with NONO, required for the formation of nuclear paraspeckles. Regulates, cooperatively with NONO and SFPQ, androgen receptor-mediated gene transcription activity in Sertoli cell line. Binds to poly(A), poly(G) and poly(U) RNA homopolymers. Regulates the circadian clock by repressing the transcriptional activator activity of the CLOCK-ARNTL/BMAL1 heterodimer. Plays a role in the regulation of DNA virus-mediated innate immune response by assembling into the HDP-RNP complex, a complex that serves as a platform for IRF3 phosphorylation and subsequent innate immune response activation through the cGAS-STING pathway.[UniProtKB/Swiss-Prot Function]
*Delivery time may vary from web posted schedule. Occasional delays may occur due to unforeseen complexities in the preparation of your product. International customers may expect an additional 1-2 weeks in shipping.

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