Mouse Hmg20a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Hmg20a
Locus ID	66867
Kit Components	GA206998G1, Hmg20a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA206998G2, Hmg20a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA206998G3, Hmg20a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_025812
Synonyms	1200004E06Rik; 5730490E10Rik; Hmgxb1; Ibraf
Summary	Plays a role in neuronal differentiation as chromatin-associated protein. Acts as inhibitor of HMG20B. Overcomes the repressive effects of the neuronal silencer REST and induces the activation of neuronal-specific genes. Involved in the recruitment of the histone methyltransferase KMT2A/MLL1 and consequent increased methylation of histone H3 lysine 4.[UniProtKB/Swiss-Prot Function]

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