Mouse Tmem107 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Tmem107
Locus ID	66910
Kit Components	GA207019G1, Tmem107 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207019G2, Tmem107 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207019G3, Tmem107 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_025838, NM_028336
Synonyms	1110004B13Rik; 2810049P21Rik
Summary	Plays a role in cilia formation and embryonic patterning. Requires for normal Sonic hedgehog (Shh) signaling in the neural tube and acts in combination with GLI2 and GLI3 to pattern ventral and intermediate neuronal cell types. During ciliogenesis regulates the ciliary transition zone localization of some MKS complex proteins (PubMed:26595381, PubMed:26518474).[UniProtKB/Swiss-Prot Function]

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