Mouse Trmt6 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Trmt6
Locus ID	66926
Kit Components	GA207030G1, Trmt6 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207030G2, Trmt6 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207030G3, Trmt6 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_175113, NM_001356442, NM_001356443, NM_001356444
Synonyms	3300001M20Rik; AU016412; AW492787; CGI-09; mKIAA1153
Summary	Substrate-binding subunit of tRNA (adenine-N(1)-)-methyltransferase, which catalyzes the formation of N(1)-methyladenine at position 58 (m1A58) in initiator methionyl-tRNA. Together with the TRMT61A catalytic subunit, part of a mRNA N(1)-methyltransferase complex that mediates methylation of adenosine residues at the N(1) position of a small subset of mRNAs: N(1) methylation takes place in tRNA T-loop-like structures of mRNAs and is only present at low stoichiometries.[UniProtKB/Swiss-Prot Function]

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