Mouse Edem3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Edem3
Locus ID	66967
Kit Components	GA207055G1, Edem3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207055G2, Edem3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207055G3, Edem3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001039644, NM_001311165, NM_001311166
Synonyms	2310050N11Rik
Summary	Involved in endoplasmic reticulum-associated degradation (ERAD). Accelerates the glycoprotein ERAD by proteasomes, by catalyzing mannose trimming from Man8GlcNAc2 to Man7GlcNAc2 in the N-glycans. Seems to have alpha 1,2-mannosidase activity.[UniProtKB/Swiss-Prot Function]

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