Mouse Riok2 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Riok2
Locus ID	67045
Kit Components	GA207105G1, Riok2 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207105G2, Riok2 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207105G3, Riok2 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_025934
Synonyms	2010110K24Rik; 2410085M17Rik
Summary	Serine/threonine-protein kinase involved in the final steps of cytoplasmic maturation of the 40S ribosomal subunit. Involved in export of the 40S pre-ribosome particles (pre-40S) from the nucleus to the cytoplasm. Its kinase activity is required for the release of NOB1, PNO1 and LTV1 from the late pre-40S and the processing of 18S-E pre-rRNA to the mature 18S rRNA. May regulate the timing of the metaphase-anaphase transition during mitotic progression, and its phosphorylation, may regulates this function.[UniProtKB/Swiss-Prot Function]

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