Mouse Trak1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Trak1
Locus ID	67095
Kit Components	GA207135G1, Trak1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207135G2, Trak1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207135G3, Trak1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_175114, NM_001357968, NM_001357969, NM_001357970, NM_001357972, NM_001357973, NR_152160
Synonyms	2310001H13Rik; AI413908; AI467545; hyrt; mKIAA1042
Summary	Involved in the regulation of endosome-to-lysosome trafficking, including endocytic trafficking of EGF-EGFR complexes and GABA-A receptors (By similarity). Involved in mitochondrial motility (PubMed:24995978). When O-glycosylated, abolishes mitochondrial motility. Crucial for recruiting OGT to the mitochondrial surface of neuronal processes (By similarity). TRAK1 and RHOT form an essential protein complex that links KIF5 to mitochondria for light chain-independent, anterograde transport of mitochondria (By similarity).[UniProtKB/Swiss-Prot Function]

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