Mouse Washc3 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Washc3
Locus ID	67282
Kit Components	GA207241G1, Washc3 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207241G2, Washc3 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207241G3, Washc3 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001122960, NM_026070, NM_027487
Synonyms	2900091E11Rik; 5730495F03Rik; Ccdc53
Summary	Acts at least in part as component of the WASH core complex whose assembly at the surface of endosomes seems to inhibit WASH nucleation-promoting factor (NPF) activity in recruiting and activating the Arp2/3 complex to induce actin polymerization, and which is involved in regulation of the fission of tubules that serve as transport intermediates during endosome sorting.[UniProtKB/Swiss-Prot Function]

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