Mouse C1qtnf12 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	C1qtnf12
Locus ID	67389
Kit Components	GA207301G1, C1qtnf12 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207301G2, C1qtnf12 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207301G3, C1qtnf12 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026125
Synonyms	1110035L05Rik; alipolin; C1qdc2; CTRP12
Summary	Insulin-sensitizing adipocyte-secreted protein (adipokine) that regulates glucose metabolism in liver and adipose tissue. Promotes glucose uptake in adipocytes and suppresses de novo glucose production in hepatocytes via the PI3K-Akt signaling pathway. Administration lead to reduction of blood glucose. Able to attenuate inflammation in fat tissue (PubMed:21849507, PubMed:22275362).[UniProtKB/Swiss-Prot Function]

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