Mouse Pdlim7 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Pdlim7
Locus ID	67399
Kit Components	GA207308G1, Pdlim7 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207308G2, Pdlim7 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207308G3, Pdlim7 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001114087, NM_001114088, NM_026131, NR_104287
Synonyms	LMP
Summary	May function as a scaffold on which the coordinated assembly of proteins can occur. May play a role as an adapter that, via its PDZ domain, localizes LIM-binding proteins to actin filaments of both skeletal muscle and nonmuscle tissues. Involved in both of the two fundamental mechanisms of bone formation, direct bone formation (e.g. embryonic flat bones mandible and cranium), and endochondral bone formation (e.g. embryonic long bone development). Plays a role during fracture repair. Involved in BMP6 signaling pathway (By similarity).[UniProtKB/Swiss-Prot Function]

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