Mouse Coq8a activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Coq8a
Locus ID	67426
Kit Components	GA207320G1, Coq8a gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207320G2, Coq8a gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207320G3, Coq8a gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001163290, NM_023341, NM_001359268, NM_001359269
Synonyms	4632432J16Rik; Adck3; AI462003; Cabc1; mKIAA0451
Summary	Atypical kinase involved in the biosynthesis of coenzyme Q, also named ubiquinone, an essential lipid-soluble electron transporter for aerobic cellular respiration (PubMed:27499294). Its substrate specificity is unclear: does not show any protein kinase activity (PubMed:27499294). Probably acts as a small molecule kinase, possibly a lipid kinase that phosphorylates a prenyl lipid in the ubiquinone biosynthesis pathway, as suggested by its ability to bind coenzyme Q lipid intermediates (By similarity). Shows an unusual selectivity for binding ADP over ATP (By similarity).[UniProtKB/Swiss-Prot Function]

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