Mouse Klhl13 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Klhl13
Locus ID	67455
Kit Components	GA207339G1, Klhl13 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207339G2, Klhl13 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207339G3, Klhl13 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_001290476, NM_001310466, NM_026167
Synonyms	1200009K10Rik; AI451128; Bklhd2; D130072F20Rik
Summary	Substrate-specific adapter of a BCR (BTB-CUL3-RBX1) E3 ubiquitin-protein ligase complex required for mitotic progression and cytokinesis. The BCR(KLHL9-KLHL13) E3 ubiquitin ligase complex mediates the ubiquitination of AURKB and controls the dynamic behavior of AURKB on mitotic chromosomes and thereby coordinates faithful mitotic progression and completion of cytokinesis (By similarity).[UniProtKB/Swiss-Prot Function]

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