Mouse Slc47a1 activation kit by CRISPRa

Specifications

Product Data
Format	3 gRNAs (5ug each), 1 scramble ctrl (10ug) and 1 enhancer vector (10ug)
Symbol	Slc47a1
Locus ID	67473
Kit Components	GA207352G1, Slc47a1 gRNA vector 1 in pCas-Guide-GFP-CRISPRa GA207352G2, Slc47a1 gRNA vector 2 in pCas-Guide-GFP-CRISPRa GA207352G3, Slc47a1 gRNA vector 3 in pCas-Guide-GFP-CRISPRa 1 CRISPRa-Enhancer vector, SKU GE100056 1 CRISPRa scramble vector, SKU GE100077
Reference Data
RefSeq	NM_026183
Synonyms	1300013J15Rik; AI036982; MATE1; mMATE1
Summary	Solute transporter for tetraethylammonium (TEA), 1-methyl-4-phenylpyridinium (MPP), cimetidine, N-methylnicotinamide (NMN), metformin, creatinine, guanidine, procainamide, topotecan, estrone sulfate, acyclovir, ganciclovir and also the zwitterionic cephalosporin, cephalexin and cephradin. Seems to also play a role in the uptake of oxaliplatin (a new platinum anticancer agent). Able to transport paraquat (PQ or N,N-dimethyl-4-4'-bipiridinium); a widely used herbicid. Responsible for the secretion of cationic drugs across the brush border membranes (By similarity).[UniProtKB/Swiss-Prot Function]

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